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KMID : 1200020220460010154
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Diabetes & Metabolism Journal
2022 Volume.46 No. 1 p.154 ~ p.159
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Do-It-Yourself Open Artificial Pancreas System in Children and Adolescents with Type 1 Diabetes Mellitus: Real-World Data
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Choi Min-Sun
Lee Seung-Hyun
Kim Ji-Won
Kim Gyu-Ri
Park Sung-Min
Kim Jae-Hyeon
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Abstract
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Few studies have been conducted among Asian children and adolescents with type 1 diabetes mellitus (T1DM) using do-it-yourself artificial pancreas system (DIY-APS). We evaluated real-world data of pediatric T1DM patients using DIY-APS. Data were obtained for 10 patients using a DIY-APS with algorithms. We collected sensor glucose and insulin delivery data from each participant for a period of 4 weeks. Average glycosylated hemoglobin was 6.2%±0.3%. The mean percentage of time that glucose level remained in the target range of 70 to 180 mg/dL was 82.4%±7.8%. Other parameters including time above range, time below range and mean glucose were also within the recommended level, similar to previous commercial and DIY-APS studies. However, despite meeting the target range, unadjusted gaps were still observed between the median basal setting and temporary basal insulin, which should be handled by healthcare providers.
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KEYWORD
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Algorithms, Diabetes mellitus, type 1, Insulin infusion system, Pancreas, artificial
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